Chemical profiling and biological properties of Neolitsea kedahense Gamble essential oils

Nor Akmalazura Jani, Hasnah Mohd Sirat, Farediah Ahmad, Nor Azah Mohamad Ali, Mailina Jamil

Research output: Contribution to journalArticle

Abstract

Hydrodistillation of the fresh stem and leaf of Neolitsea kedahense Gamble, collected from Gunung Jerai, Malaysia followed by the GC-FID and GC-MS analysis revealed the detection of a total of 47 constituents of which 28 (86.4%) from the stem and 31 (96.4%) constituents from the leaf. δ-Cadinene (17.4%), 1-epi-cubenol (11.8%), cyperotundone (9.0%), cis-cadin-4-en-7-ol (7.7%), τ-cadinol (7.1%) and α-cadinol (7.1%) were the principle constituents in the stem oil, whereas β-caryophyllene (18.9%), bicyclogermacrene (18.6%) and trans-muurola-4(14),5-diene (9.8%) were the major constituents in the leaf oil. Among the identified constituents, three constituents namely 7-epi-α-selinene, junenol and cis-cadin-4-en-7-ol have not been found previously from Neolitsea oils. The stem and leaf oils were screened for their α-glucosidase inhibitory and antibacterial activities. Both oils displayed potential α-glucosidase inhibitory activity, while the stem oil possessed weak antibacterial activity against Bacillus subtilis.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalNatural Product Research
DOIs
StateAccepted/In press - 25 Feb 2017

Fingerprint

stems
Volatile Oils
Oils
oils
Neolitsea
leaf oils
alpha-glucosidase
leaves
alpha-Glucosidases
beta-caryophyllene
Bacillus subtilis
Malaysia
essential oils
Strabismus

Keywords

  • antibacterial
  • Neolitsea kedahense Gamble
  • α-glucosidase inhibitory

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

Cite this

Chemical profiling and biological properties of Neolitsea kedahense Gamble essential oils. / Jani, Nor Akmalazura; Sirat, Hasnah Mohd; Ahmad, Farediah; Mohamad Ali, Nor Azah; Jamil, Mailina.

In: Natural Product Research, 25.02.2017, p. 1-4.

Research output: Contribution to journalArticle

Jani, Nor Akmalazura; Sirat, Hasnah Mohd; Ahmad, Farediah; Mohamad Ali, Nor Azah; Jamil, Mailina / Chemical profiling and biological properties of Neolitsea kedahense Gamble essential oils.

In: Natural Product Research, 25.02.2017, p. 1-4.

Research output: Contribution to journalArticle

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